{
  "name": "UK Dog Food Allergy Data",
  "version": "1.0.0",
  "published": "2026-08-05",
  "next_review": "2027-02-05",
  "rows": [
    {
      "id": "vet-presentations-prevalence",
      "topic": "prevalence",
      "figure": "1–2%",
      "denominator": "Dogs brought to a vet for any reason",
      "sample": "22 canine studies (critically appraised topic)",
      "finding": "Estimated prevalence of cutaneous adverse food reactions in this population.",
      "confidence": "well-evidenced",
      "source": {
        "authors": "Olivry & Mueller",
        "year": 2017,
        "doi": "10.1186/s12917-017-0973-z"
      }
    },
    {
      "id": "atopic-dermatitis-prevalence",
      "topic": "prevalence",
      "figure": "9–50%",
      "denominator": "Dogs already diagnosed with atopic dermatitis",
      "sample": "22 canine studies (critically appraised topic)",
      "finding": "Estimated prevalence of cutaneous adverse food reactions in this selected population.",
      "confidence": "well-evidenced",
      "source": {
        "authors": "Olivry & Mueller",
        "year": 2017,
        "doi": "10.1186/s12917-017-0973-z"
      }
    },
    {
      "id": "food-induced-atopic-dermatitis",
      "topic": "prevalence",
      "figure": "172 of 843 (about 20%)",
      "denominator": "Dogs with atopic dermatitis in one prospective cohort",
      "sample": "843 dogs with atopic dermatitis; 1,096 pruritic dogs enrolled",
      "finding": "Dogs classified with food-induced atopic dermatitis in this cohort.",
      "confidence": "well-evidenced",
      "source": {
        "authors": "Favrot et al.",
        "year": 2010,
        "doi": "10.1111/j.1365-3164.2009.00758.x"
      }
    },
    {
      "id": "reported-allergen-order",
      "topic": "reported food sources",
      "figure": "Beef, dairy, chicken, then wheat",
      "denominator": "Confirmed cutaneous adverse food-reaction cases",
      "sample": "297 dogs pooled across studies",
      "finding": "Most commonly reported food sources, in rank order. This is not population risk or inherent allergenicity.",
      "confidence": "well-evidenced",
      "source": {
        "authors": "Mueller, Olivry & Prélaud",
        "year": 2016,
        "doi": "10.1186/s12917-016-0633-8"
      }
    },
    {
      "id": "reported-lamb-cases",
      "topic": "reported food sources",
      "figure": "14 of 297 (about 5%)",
      "denominator": "Confirmed cutaneous adverse food-reaction cases",
      "sample": "297 dogs pooled across studies",
      "finding": "Reported lamb cases. This does not establish lamb as a population risk.",
      "confidence": "well-evidenced",
      "source": {
        "authors": "Mueller, Olivry & Prélaud",
        "year": 2016,
        "doi": "10.1186/s12917-016-0633-8"
      }
    },
    {
      "id": "reported-egg-cases",
      "topic": "reported food sources",
      "figure": "About 4%; eighth on the list",
      "denominator": "Confirmed cutaneous adverse food-reaction cases",
      "sample": "297 dogs pooled across studies",
      "finding": "Reported egg cases and rank. This is not evidence that egg is safe for an individual dog.",
      "confidence": "well-evidenced",
      "source": {
        "authors": "Mueller, Olivry & Prélaud",
        "year": 2016,
        "doi": "10.1186/s12917-016-0633-8"
      }
    },
    {
      "id": "elimination-diet-week-five",
      "topic": "diet trial",
      "figure": "More than 80% by week 5",
      "denominator": "Dogs on an elimination diet in the included studies",
      "sample": "Pooled remission data; no single published denominator",
      "finding": "Complete remission of signs by week 5 in the reviewed studies.",
      "confidence": "well-evidenced",
      "source": {
        "authors": "Olivry, Mueller & Prélaud",
        "year": 2015,
        "doi": "10.1186/s12917-015-0541-3"
      }
    },
    {
      "id": "elimination-diet-week-eight",
      "topic": "diet trial",
      "figure": "More than 90% by week 8",
      "denominator": "Dogs on an elimination diet in the included studies",
      "sample": "Pooled remission data; no single published denominator",
      "finding": "Complete remission of signs by week 8 in the reviewed studies; the review recommends at least 8 weeks to identify more than 90% of cases.",
      "confidence": "well-evidenced",
      "source": {
        "authors": "Olivry, Mueller & Prélaud",
        "year": 2015,
        "doi": "10.1186/s12917-015-0541-3"
      }
    },
    {
      "id": "partial-hydrolysate-reactions",
      "topic": "hydrolysed diets",
      "figure": "Up to 50%",
      "denominator": "Sensitised dogs fed a partial hydrolysate made from a protein they reacted to",
      "sample": "3 controlled studies within an 11-study systematic review",
      "finding": "Dogs that worsened in the included controlled studies. Hydrolysis can reduce allergenicity but does not eliminate it in every sensitised dog.",
      "confidence": "well-evidenced",
      "source": {
        "authors": "Olivry & Bizikova",
        "year": 2010,
        "doi": "10.1111/j.1365-3164.2009.00761.x"
      }
    },
    {
      "id": "age-and-breed-signal",
      "topic": "signalment",
      "figure": "825 dogs across 22 articles",
      "denominator": "Dogs with adverse food reactions in the included articles",
      "sample": "825 dogs; 22 articles",
      "finding": "Cases occurred across breeds and ages. Breed findings varied substantially between studies, so they are a weak signal rather than a prediction rule.",
      "confidence": "mixed evidence",
      "source": {
        "authors": "Olivry & Mueller",
        "year": 2019,
        "doi": "10.1186/s12917-019-1880-2"
      }
    },
    {
      "id": "exposure-precedes-onset",
      "topic": "exposure history",
      "figure": "Prior exposure is the norm",
      "denominator": "Dogs with adverse food reactions described in the review",
      "sample": "Narrative review of the canine and feline literature",
      "finding": "Dogs usually eat a food for a long period before reacting to it, so a food that has been in the bowl for years is not exonerated by familiarity. This is the counter-intuitive point owners most often get wrong when they rule out the long-standing food first.",
      "confidence": "well-evidenced",
      "source": {
        "authors": "Verlinden, Hesta, Millet & Janssens",
        "year": 2006,
        "doi": "10.1080/10408390591001117"
      }
    }
  ]
}